To advance the state of the art of its proprietary photochromic technology used in Transitions® eyewear and speed its time-to-market, PPG Industries enlisted the help of high performance computing. Advancing photochromic technology, which allows lenses to change from clear to dark and block harmful ultraviolet rays, involves complex modeling and simulation of molecules at the atomic and quantum levels. By enlisting the help of the NSF-funded Pittsburgh Supercomputing Center and its powerful high performance computing capabilities, PPG’s R&D organization was able to rapidly create the next generation of photochromic dyes, and move out in front of its competition.